Allelic complementation between MHC haplotypes B(Q) and B17 increases regression of Rous sarcomas
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منابع مشابه
Allelic Complementation Between MHC Haplotypes BQ and B17ËIncreases Regression o
Major histocompatibility (B) complex haplotypes BQ and B17 were examined for their effect on Rous sarcoma outcome. Pedigree matings of BQB17 chickens from the second backcross generation (BC2) of Line UCD 001 (BQBQ) mated to Line UCD 003 (B17B17) produced progeny with genotypes BQBQ, BQB17, and B17B17. Sixweek-old chickens were injected with subgroup A Rous sarcoma virus (RSV). The tumors were ...
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Tumors were induced in Regional Poultry Research Laboratory line 6 chickens inoculated in the wing web with Rous sarcoma virus the Bryan high-liter strain of pseudotype, at 1, 14, and 28 days of age. Tumor regression failed to occur in chicks inoculated at 1 and 14 days of age, but an incidence of regression of 50% was observed in chicks inocu lated at 28 days of age. Chick survival time postin...
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The control of gene regulation within the major histocompatibility complex (MHC) remains poorly understood, despite several expression quantitative trait loci (eQTL) studies revealing an association of MHC gene expression with independent tag-single nucleotide polymorphisms (SNPs). MHC haplotype variation may exert a greater effect on gene expression phenotype than specific single variants. To ...
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Newborn hamsters were injected subcutaneously with a suspension of finely minced Rous chicken sarcoma (Schmidt-Ruppin strain). After an interval of about 2 weeks, progressively growing sarcomas developed at the site of injection in almost all animals. Also in adult hamsters inoculated intramuscularly with the same material sarcomas developed at the site of injection within 2 to 4 months. Second...
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ژورنال
عنوان ژورنال: Poultry Science
سال: 2000
ISSN: 0032-5791
DOI: 10.1093/ps/79.12.1736